Anti-HIV-1 Nanobody-IgG1 Constructs With Improved Neutralization Potency and the Ability to Mediate Fc Effector Functions

The most effective treatment for HIV-1, antiretroviral therapy, suppresses viral replication and averts the disease from progression. Nonetheless, there is a need for alternative treatments as it requires daily administration with the possibility of side effects and occurrence of drug resistance. Br...

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Detalles Bibliográficos
Autores principales: Schriek, Angela I., van Haaren, Marlies M., Poniman, Meliawati, Dekkers, Gillian, Bentlage, Arthur E. H., Grobben, Marloes, Vidarsson, Gestur, Sanders, Rogier W., Verrips, Theo, Geijtenbeek, Teunis B. H., Heukers, Raimond, Kootstra, Neeltje A., de Taeye, Steven W., van Gils, Marit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150821/
https://www.ncbi.nlm.nih.gov/pubmed/35651621
http://dx.doi.org/10.3389/fimmu.2022.893648

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