A cytotoxic-skewed immune set point predicts low neutralizing antibody levels after Zika virus infection

Although generating high neutralizing antibody levels is a key component of protective immunity after acute viral infection or vaccination, little is known about why some individuals generate high versus low neutralizing antibody titers. Here, we leverage the high-dimensional single-cell profiling c...

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Detalles Bibliográficos
Autores principales: McCarthy, Elizabeth E., Odorizzi, Pamela M., Lutz, Emma, Smullin, Carolyn P., Tenvooren, Iliana, Stone, Mars, Simmons, Graham, Hunt, Peter W., Feeney, Margaret E., Norris, Philip J., Busch, Michael P., Spitzer, Matthew H., Rutishauser, Rachel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151348/
https://www.ncbi.nlm.nih.gov/pubmed/35584677
http://dx.doi.org/10.1016/j.celrep.2022.110815

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