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Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation

Currently, approximately 80,000 chemicals are used in commerce. Most have little-to-no toxicity information. The U.S. Toxicology in the 21st Century (Tox21) program has conducted a battery of in vitro assays using a quantitative high-throughput screening (qHTS) platform to gain toxicity information...

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Detalles Bibliográficos
Autores principales:	Ooka, Masato, Zhao, Jinghua, Shah, Pranav, Travers, Jameson, Klumpp-Thomas, Carleen, Xu, Xin, Huang, Ruili, Ferguson, Stephen, Witt, Kristine L., Smith-Roe, Stephanie L., Simeonov, Anton, Xia, Menghang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Toxicokinetics and Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151520/ https://www.ncbi.nlm.nih.gov/pubmed/35435491 http://dx.doi.org/10.1007/s00204-022-03291-5

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