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Ogilvie’s syndrome—is there a cutoff diameter to proceed with upfront surgery?

PURPOSE: Although Ogilvie’s syndrome was first described about 70 years ago, its etiology and pathogenesis are still not fully understood. But more importantly, it is also not clear when to approach which therapeutic strategy. METHODS: Patients who were diagnosed with Ogilvie’s syndrome at our insti...

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Autores principales: Joechle, Katharina, Guenzle, Jessica, Utzolino, Stefan, Fichtner-Feigl, Stefan, Kousoulas, Lampros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151542/
https://www.ncbi.nlm.nih.gov/pubmed/35020083
http://dx.doi.org/10.1007/s00423-021-02407-2
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author Joechle, Katharina
Guenzle, Jessica
Utzolino, Stefan
Fichtner-Feigl, Stefan
Kousoulas, Lampros
author_facet Joechle, Katharina
Guenzle, Jessica
Utzolino, Stefan
Fichtner-Feigl, Stefan
Kousoulas, Lampros
author_sort Joechle, Katharina
collection PubMed
description PURPOSE: Although Ogilvie’s syndrome was first described about 70 years ago, its etiology and pathogenesis are still not fully understood. But more importantly, it is also not clear when to approach which therapeutic strategy. METHODS: Patients who were diagnosed with Ogilvie’s syndrome at our institution in a 17-year time period (2002–2019) were included and retrospectively evaluated regarding different therapeutical strategies: conservative, endoscopic, or surgical. RESULTS: The study included 71 patients with 21 patients undergoing conservative therapy, 25 patients undergoing endoscopic therapy, and 25 patients undergoing surgery. However, 38% of patients (n = 8) who were primarily addressed for conservative management failed and had to undergo endoscopy or even surgery. Similarly, 8 patients (32%) with primarily endoscopic treatment had to proceed for surgery. In logistic regression analysis, only a colon diameter ≥ 11 cm (p = 0.01) could predict a lack of therapeutic success by endoscopic treatment. Ninety-day mortality and overall survival were comparable between the groups. CONCLUSION: As conservative and endoscopic management fail in about one-third of patients, a cutoff diameter ≥ 11 cm may be an adequate parameter to evaluate surgical therapy.
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spelling pubmed-91515422022-06-01 Ogilvie’s syndrome—is there a cutoff diameter to proceed with upfront surgery? Joechle, Katharina Guenzle, Jessica Utzolino, Stefan Fichtner-Feigl, Stefan Kousoulas, Lampros Langenbecks Arch Surg Original Article PURPOSE: Although Ogilvie’s syndrome was first described about 70 years ago, its etiology and pathogenesis are still not fully understood. But more importantly, it is also not clear when to approach which therapeutic strategy. METHODS: Patients who were diagnosed with Ogilvie’s syndrome at our institution in a 17-year time period (2002–2019) were included and retrospectively evaluated regarding different therapeutical strategies: conservative, endoscopic, or surgical. RESULTS: The study included 71 patients with 21 patients undergoing conservative therapy, 25 patients undergoing endoscopic therapy, and 25 patients undergoing surgery. However, 38% of patients (n = 8) who were primarily addressed for conservative management failed and had to undergo endoscopy or even surgery. Similarly, 8 patients (32%) with primarily endoscopic treatment had to proceed for surgery. In logistic regression analysis, only a colon diameter ≥ 11 cm (p = 0.01) could predict a lack of therapeutic success by endoscopic treatment. Ninety-day mortality and overall survival were comparable between the groups. CONCLUSION: As conservative and endoscopic management fail in about one-third of patients, a cutoff diameter ≥ 11 cm may be an adequate parameter to evaluate surgical therapy. Springer Berlin Heidelberg 2022-01-12 2022 /pmc/articles/PMC9151542/ /pubmed/35020083 http://dx.doi.org/10.1007/s00423-021-02407-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Joechle, Katharina
Guenzle, Jessica
Utzolino, Stefan
Fichtner-Feigl, Stefan
Kousoulas, Lampros
Ogilvie’s syndrome—is there a cutoff diameter to proceed with upfront surgery?
title Ogilvie’s syndrome—is there a cutoff diameter to proceed with upfront surgery?
title_full Ogilvie’s syndrome—is there a cutoff diameter to proceed with upfront surgery?
title_fullStr Ogilvie’s syndrome—is there a cutoff diameter to proceed with upfront surgery?
title_full_unstemmed Ogilvie’s syndrome—is there a cutoff diameter to proceed with upfront surgery?
title_short Ogilvie’s syndrome—is there a cutoff diameter to proceed with upfront surgery?
title_sort ogilvie’s syndrome—is there a cutoff diameter to proceed with upfront surgery?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151542/
https://www.ncbi.nlm.nih.gov/pubmed/35020083
http://dx.doi.org/10.1007/s00423-021-02407-2
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