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Sigmoid volvulus: outcomes of treatment and predictors of morbidity and mortality

PURPOSE: To analyze the treatment outcomes for sigmoid volvulus (SV) and identify risk factors of complications and mortality. METHODS: Observational study of all consecutive adult patients diagnosed with SV who were admitted from January 2000 to December 2020 in a tertiary university institution fo...

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Autores principales: Moro-Valdezate, David, Martín-Arévalo, José, Pla-Martí, Vicente, García-Botello, Stephanie, Izquierdo-Moreno, Ana, Pérez-Santiago, Leticia, Pedrós-Giménez, Jorge Manuel, Villagrasa, Rosana, Peña, Andrés, Espí-Macías, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151547/
https://www.ncbi.nlm.nih.gov/pubmed/35028738
http://dx.doi.org/10.1007/s00423-022-02428-5
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author Moro-Valdezate, David
Martín-Arévalo, José
Pla-Martí, Vicente
García-Botello, Stephanie
Izquierdo-Moreno, Ana
Pérez-Santiago, Leticia
Pedrós-Giménez, Jorge Manuel
Villagrasa, Rosana
Peña, Andrés
Espí-Macías, Alejandro
author_facet Moro-Valdezate, David
Martín-Arévalo, José
Pla-Martí, Vicente
García-Botello, Stephanie
Izquierdo-Moreno, Ana
Pérez-Santiago, Leticia
Pedrós-Giménez, Jorge Manuel
Villagrasa, Rosana
Peña, Andrés
Espí-Macías, Alejandro
author_sort Moro-Valdezate, David
collection PubMed
description PURPOSE: To analyze the treatment outcomes for sigmoid volvulus (SV) and identify risk factors of complications and mortality. METHODS: Observational study of all consecutive adult patients diagnosed with SV who were admitted from January 2000 to December 2020 in a tertiary university institution for conservative management, urgent or elective surgery. Primary outcomes were 30-day postoperative morbidity, mortality and 2-year overall survival (OS), including analysis of risk factors for postoperative morbidity or mortality and prognostic factors for 2-year OS. RESULTS: A total of 92 patients were included. Conservative management was performed in 43 cases (46.7%), 27 patients (29.4%) underwent emergent surgery and 22 (23.9%) were scheduled for elective surgery. Successful decompression was achieved in 87.8% of cases, but the recurrence rate was 47.2%. Mortality rates following episodes were higher for conservative treatment than for urgent or elective surgery (37.2%, 22.2%, 9.1%, respectively; p = 0.044). ASA score > III was an independent risk factor for complications (OR = 5.570, 95% CI = 1.740–17.829, p < 0.001) and mortality (OR = 6.139, 95% CI = 2.629–14.335, p < 0.001) in the 30 days after admission. Patients who underwent elective surgery showed higher 2-year OS than those with conservative treatment (p = 0.011). Elective surgery (HR = 2.604, 95% CI = 1.185–5.714, p = 0.017) and ASA score > III (HR = 0.351, 95% CI = 0.192–0.641, p = 0.001) were independent prognostic factors for 2-year OS. CONCLUSION: Successful endoscopic decompression can be achieved in most SV patients, but with the drawbacks of high recurrence, morbidity and mortality rates. Concurrent severe comorbidities and conservative treatment were independent prognostic factors for morbidity and survival in SV.
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spelling pubmed-91515472022-06-01 Sigmoid volvulus: outcomes of treatment and predictors of morbidity and mortality Moro-Valdezate, David Martín-Arévalo, José Pla-Martí, Vicente García-Botello, Stephanie Izquierdo-Moreno, Ana Pérez-Santiago, Leticia Pedrós-Giménez, Jorge Manuel Villagrasa, Rosana Peña, Andrés Espí-Macías, Alejandro Langenbecks Arch Surg Original Article PURPOSE: To analyze the treatment outcomes for sigmoid volvulus (SV) and identify risk factors of complications and mortality. METHODS: Observational study of all consecutive adult patients diagnosed with SV who were admitted from January 2000 to December 2020 in a tertiary university institution for conservative management, urgent or elective surgery. Primary outcomes were 30-day postoperative morbidity, mortality and 2-year overall survival (OS), including analysis of risk factors for postoperative morbidity or mortality and prognostic factors for 2-year OS. RESULTS: A total of 92 patients were included. Conservative management was performed in 43 cases (46.7%), 27 patients (29.4%) underwent emergent surgery and 22 (23.9%) were scheduled for elective surgery. Successful decompression was achieved in 87.8% of cases, but the recurrence rate was 47.2%. Mortality rates following episodes were higher for conservative treatment than for urgent or elective surgery (37.2%, 22.2%, 9.1%, respectively; p = 0.044). ASA score > III was an independent risk factor for complications (OR = 5.570, 95% CI = 1.740–17.829, p < 0.001) and mortality (OR = 6.139, 95% CI = 2.629–14.335, p < 0.001) in the 30 days after admission. Patients who underwent elective surgery showed higher 2-year OS than those with conservative treatment (p = 0.011). Elective surgery (HR = 2.604, 95% CI = 1.185–5.714, p = 0.017) and ASA score > III (HR = 0.351, 95% CI = 0.192–0.641, p = 0.001) were independent prognostic factors for 2-year OS. CONCLUSION: Successful endoscopic decompression can be achieved in most SV patients, but with the drawbacks of high recurrence, morbidity and mortality rates. Concurrent severe comorbidities and conservative treatment were independent prognostic factors for morbidity and survival in SV. Springer Berlin Heidelberg 2022-01-14 2022 /pmc/articles/PMC9151547/ /pubmed/35028738 http://dx.doi.org/10.1007/s00423-022-02428-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Moro-Valdezate, David
Martín-Arévalo, José
Pla-Martí, Vicente
García-Botello, Stephanie
Izquierdo-Moreno, Ana
Pérez-Santiago, Leticia
Pedrós-Giménez, Jorge Manuel
Villagrasa, Rosana
Peña, Andrés
Espí-Macías, Alejandro
Sigmoid volvulus: outcomes of treatment and predictors of morbidity and mortality
title Sigmoid volvulus: outcomes of treatment and predictors of morbidity and mortality
title_full Sigmoid volvulus: outcomes of treatment and predictors of morbidity and mortality
title_fullStr Sigmoid volvulus: outcomes of treatment and predictors of morbidity and mortality
title_full_unstemmed Sigmoid volvulus: outcomes of treatment and predictors of morbidity and mortality
title_short Sigmoid volvulus: outcomes of treatment and predictors of morbidity and mortality
title_sort sigmoid volvulus: outcomes of treatment and predictors of morbidity and mortality
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151547/
https://www.ncbi.nlm.nih.gov/pubmed/35028738
http://dx.doi.org/10.1007/s00423-022-02428-5
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