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A TMT-based shotgun proteomics uncovers overexpression of thrombospondin 1 as a contributor in pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome

Hepatic sinusoidal obstruction disease (HSOS) is a rare but life-threatening vascular liver disease. However, its underlying mechanism and molecular changes in HSOS are largely unknown, thus greatly hindering the development of its effective treatment. Hepatic sinusoidal endothelial cells (HSECs) ar...

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Detalles Bibliográficos
Autores principales:	Wang, Weiqian, Chen, Yan, Yin, Yue, Wang, Xunjiang, Ye, Xuanling, Jiang, Kaiyuan, Zhang, Yi, Zhang, Jiwei, Zhang, Wei, Zhuge, Yuzheng, Chen, Li, Peng, Chao, Xiong, Aizhen, Yang, Li, Wang, Zhengtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Toxicogenomics and Omics Technologies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151551/ https://www.ncbi.nlm.nih.gov/pubmed/35357534 http://dx.doi.org/10.1007/s00204-022-03281-7

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