Complementary omics strategies to dissect p53 signaling networks under nutrient stress

Signaling trough p53is a major cellular stress response mechanism and increases upon nutrient stresses such as starvation. Here, we show in a human hepatoma cell line that starvation leads to robust nuclear p53 stabilization. Using BioID, we determine the cytoplasmic p53 interaction network within t...

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Detalles Bibliográficos
Autores principales: Galhuber, Markus, Michenthaler, Helene, Heininger, Christoph, Reinisch, Isabel, Nössing, Christoph, Krstic, Jelena, Kupper, Nadja, Moyschewitz, Elisabeth, Auer, Martina, Heitzer, Ellen, Ulz, Peter, Birner-Gruenberger, Ruth, Liesinger, Laura, Lenihan-Geels, Georgia Ngawai, Oster, Moritz, Spreitzer, Emil, Zenezini Chiozzi, Riccardo, Schulz, Tim J., Schupp, Michael, Madl, Tobias, Heck, Albert J. R., Prokesch, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151573/
https://www.ncbi.nlm.nih.gov/pubmed/35635656
http://dx.doi.org/10.1007/s00018-022-04345-8

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