Structural variants shape the genomic landscape and clinical outcome of multiple myeloma

Deciphering genomic architecture is key to identifying novel disease drivers and understanding the mechanisms underlying myeloma initiation and progression. In this work, using the CoMMpass dataset, we show that structural variants (SV) occur in a nonrandom fashion throughout the genome with an incr...

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Detalles Bibliográficos
Autores principales: Ashby, Cody, Boyle, Eileen M., Bauer, Michael A., Mikulasova, Aneta, Wardell, Christopher P., Williams, Louis, Siegel, Ariel, Blaney, Patrick, Braunstein, Marc, Kaminetsky, David, Keats, Jonathan, Maura, Francesco, Landgren, Ola, Walker, Brian A., Davies, Faith E., Morgan, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151656/
https://www.ncbi.nlm.nih.gov/pubmed/35637217
http://dx.doi.org/10.1038/s41408-022-00673-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151656/
https://www.ncbi.nlm.nih.gov/pubmed/35637217
http://dx.doi.org/10.1038/s41408-022-00673-x

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