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Harnessing allogeneic NK cells: improving outcomes with tailored donor lymphocyte infusion

Since researchers first began to uncover the mechanisms underlying allogeneic transplantation, the focus has been on T cells. T cells are a major instigator of graft-versus-host disease (GVHD). The clear association between GVHD occurrence and subsequent reduction in relapse supported concentrating...

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Detalles Bibliográficos
Autor principal: McCurdy, Shannon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151684/
https://www.ncbi.nlm.nih.gov/pubmed/35642633
http://dx.doi.org/10.1172/JCI160584