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Deficiency in the zinc transporter ZIP8 impairs epithelia renewal and enhances lung fibrosis

Although aging and lung injury are linked to the development of idiopathic pulmonary fibrosis (IPF), the underlying pathognomonic processes predisposing to fibrotic lesions remain largely unknown. A deficiency in the ability of type 2 alveolar epithelial cell (AEC2) progenitors to regenerate and rep...

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Detalles Bibliográficos
Autores principales: Foster, Paul S., Tay, Hock L., Oliver, Brian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151685/
https://www.ncbi.nlm.nih.gov/pubmed/35642632
http://dx.doi.org/10.1172/JCI160595