Reprogramming dysfunctional CD8(+) T cells to promote properties associated with natural HIV control

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Virus-specific CD8(+) T cells play a central role in HIV-1 natural controllers to maintain suppressed viremia in the absence of antiretroviral therapy. These cells display a memory program that confers them stemness properties, high survival, polyfunctionality, proliferative capacity, metabolic plas...

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Detalles Bibliográficos
Autores principales: Perdomo-Celis, Federico, Passaes, Caroline, Monceaux, Valérie, Volant, Stevenn, Boufassa, Faroudy, de Truchis, Pierre, Marcou, Morgane, Bourdic, Katia, Weiss, Laurence, Jung, Corinne, Bourgeois, Christine, Goujard, Cécile, Meyer, Laurence, Müller-Trutwin, Michaela, Lambotte, Olivier, Sáez-Cirión, Asier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151687/
https://www.ncbi.nlm.nih.gov/pubmed/35380989
http://dx.doi.org/10.1172/JCI157549
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