Cargando…
Hypoxia-inducible factors: cancer progression and clinical translation
Hypoxia-inducible factors (HIFs) are master regulators of oxygen homeostasis that match O(2) supply and demand for each of the 50 trillion cells in the adult human body. Cancer cells co-opt this homeostatic system to drive cancer progression. HIFs activate the transcription of thousands of genes tha...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151701/ https://www.ncbi.nlm.nih.gov/pubmed/35642641 http://dx.doi.org/10.1172/JCI159839 |