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Four-Octyl itaconate ameliorates periodontal destruction via Nrf2-dependent antioxidant system
Periodontitis is a widespread oral disease characterized by continuous inflammation of the periodontal tissue and an irreversible alveolar bone loss, which eventually leads to tooth loss. Four-octyl itaconate (4-OI) is a cell-permeable itaconate derivative and has been recognized as a promising ther...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151820/ https://www.ncbi.nlm.nih.gov/pubmed/35637195 http://dx.doi.org/10.1038/s41368-022-00177-1 |