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Cortical D1 and D2 dopamine receptor availability modulate methylphenidate-induced changes in brain activity and functional connectivity

Dopamine signaling plays a critical role in shaping brain functional network organization and behavior. Prominent theories suggest the relative expression of D1- to D2-like dopamine receptors shapes excitatory versus inhibitory signaling, with broad consequences for cognition. Yet it remains unknown...

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Detalles Bibliográficos
Autores principales: Manza, Peter, Shokri-Kojori, Ehsan, Demiral, Şükrü Barış, Wiers, Corinde E., Zhang, Rui, Giddens, Natasha, McPherson, Katherine, Biesecker, Erin, Dennis, Evan, Johnson, Allison, Tomasi, Dardo, Wang, Gene-Jack, Volkow, Nora D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151821/
https://www.ncbi.nlm.nih.gov/pubmed/35637272
http://dx.doi.org/10.1038/s42003-022-03434-5