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PD-L1 Mediates IFNγ-Regulation of Glucose but Not of Tryptophan Metabolism in Clear Cell Renal Cell Carcinoma

The immune checkpoint programmed death-ligand 1 (PD-L1) is expressed on the cell surface of tumor cells and is key for maintaining an immunosuppressive microenvironment through its interaction with the programmed death 1 (PD-1). Clear cell renal cell carcinoma (ccRCC) is a highly immunogenic cancer...

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Detalles Bibliográficos
Autores principales: Garige, Mamatha, Ghosh, Susmita, Norris, Alexis, Li, Guangyuan, Poncet, Sarah, Chou, Chao-Kai, Wu, Wells W., Shen, Rong-Fong, Sourbier, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152103/
https://www.ncbi.nlm.nih.gov/pubmed/35656514
http://dx.doi.org/10.3389/fonc.2022.858379