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PD-L1 Mediates IFNγ-Regulation of Glucose but Not of Tryptophan Metabolism in Clear Cell Renal Cell Carcinoma
The immune checkpoint programmed death-ligand 1 (PD-L1) is expressed on the cell surface of tumor cells and is key for maintaining an immunosuppressive microenvironment through its interaction with the programmed death 1 (PD-1). Clear cell renal cell carcinoma (ccRCC) is a highly immunogenic cancer...
Autores principales: | Garige, Mamatha, Ghosh, Susmita, Norris, Alexis, Li, Guangyuan, Poncet, Sarah, Chou, Chao-Kai, Wu, Wells W., Shen, Rong-Fong, Sourbier, Carole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152103/ https://www.ncbi.nlm.nih.gov/pubmed/35656514 http://dx.doi.org/10.3389/fonc.2022.858379 |
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