Liver Ischemia and Reperfusion Induce Periportal Expression of Necroptosis Executor pMLKL Which Is Associated With Early Allograft Dysfunction After Transplantation

BACKGROUND: Early allograft dysfunction (EAD) following liver transplantation (LT) remains a major threat to the survival of liver grafts and recipients. In animal models, it is shown that hepatic ischemia-reperfusion injury (IRI) triggers phosphorylation of Mixed Lineage Kinase domain-like protein...

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Detalles Bibliográficos
Autores principales: Shi, Shaojun, Bonaccorsi-Riani, Eliano, Schurink, Ivo, van den Bosch, Thierry, Doukas, Michael, Lila, Karishma A., Roest, Henk P., Xhema, Daela, Gianello, Pierre, de Jonge, Jeroen, Verstegen, Monique M. A., van der Laan, Luc J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152120/
https://www.ncbi.nlm.nih.gov/pubmed/35655777
http://dx.doi.org/10.3389/fimmu.2022.890353

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