Gemcitabine-Loaded Albumin Nanoparticle Exerts An Antitumor Effect on Gemcitabine-Resistant Pancreatic Cancer Cells Induced by MDR1 and MRP1 Overexpression in Vitro

PURPOSE: Gemcitabine (GEM) is the first-line chemotherapeutic drug for pancreatic cancer treatment in clinical practice. However, many reasons can reduce the efficacy of GEM, among which the high expression of ATP-binding cassette (ABC) transporters is a significant factor. In this study, we aimed t...

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Detalles Bibliográficos
Autores principales: Kong, Lei, Du, Jiali, Gu, Jichun, Deng, Junyuan, Guo, Yujie, Tao, Baian, Jin, Chen, Fu, Deliang, Li, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152182/
https://www.ncbi.nlm.nih.gov/pubmed/35656085
http://dx.doi.org/10.3389/fsurg.2022.890412

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