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A Case Report and Review of the Literature: Infectious Aneurysm Formation in the Pulmonary Arteries—A Rare but Perilous Sequela of Persisting Infection With Klebsiella pneumoniae

Septic aneurysms of the pulmonary artery are rare conditions, with few cases having been reported worldwide. They are assumed to result from septic emboli that cause a local inflammatory reaction of the arterial wall, ultimately leading to degenerative changes. We report the case of a 63-year-old fe...

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Autores principales: Ruwisch, Jannik, Fischer, Bettina, Häbel, Lea, Laenger, Florian, Bollmann, Benjamin-Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152446/
https://www.ncbi.nlm.nih.gov/pubmed/35656000
http://dx.doi.org/10.3389/fmicb.2022.893737
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author Ruwisch, Jannik
Fischer, Bettina
Häbel, Lea
Laenger, Florian
Bollmann, Benjamin-Alexander
author_facet Ruwisch, Jannik
Fischer, Bettina
Häbel, Lea
Laenger, Florian
Bollmann, Benjamin-Alexander
author_sort Ruwisch, Jannik
collection PubMed
description Septic aneurysms of the pulmonary artery are rare conditions, with few cases having been reported worldwide. They are assumed to result from septic emboli that cause a local inflammatory reaction of the arterial wall, ultimately leading to degenerative changes. We report the case of a 63-year-old female patient presenting with Klebsiella pneumoniae urosepsis and first diagnosis of diabetes mellitus, who developed a life-threatening infectious pulmonary artery aneurysm secondary to bacteremia with Klebsiella pneumoniae. The patient required a lobectomy due to pulmonary hemorrhage. We review the clinical hallmarks of Klebsiella pneumoniae related septic pulmonary embolic disease and summarize currently known risk factors for the development of infectious aneurysmatic disease including diabetes mellitus and other states of immunosuppression. The featured case aims to increase the awareness for this seldom but life-threatening complication of infectious diseases such as Klebsiella pneumoniae urosepsis.
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spelling pubmed-91524462022-06-01 A Case Report and Review of the Literature: Infectious Aneurysm Formation in the Pulmonary Arteries—A Rare but Perilous Sequela of Persisting Infection With Klebsiella pneumoniae Ruwisch, Jannik Fischer, Bettina Häbel, Lea Laenger, Florian Bollmann, Benjamin-Alexander Front Microbiol Microbiology Septic aneurysms of the pulmonary artery are rare conditions, with few cases having been reported worldwide. They are assumed to result from septic emboli that cause a local inflammatory reaction of the arterial wall, ultimately leading to degenerative changes. We report the case of a 63-year-old female patient presenting with Klebsiella pneumoniae urosepsis and first diagnosis of diabetes mellitus, who developed a life-threatening infectious pulmonary artery aneurysm secondary to bacteremia with Klebsiella pneumoniae. The patient required a lobectomy due to pulmonary hemorrhage. We review the clinical hallmarks of Klebsiella pneumoniae related septic pulmonary embolic disease and summarize currently known risk factors for the development of infectious aneurysmatic disease including diabetes mellitus and other states of immunosuppression. The featured case aims to increase the awareness for this seldom but life-threatening complication of infectious diseases such as Klebsiella pneumoniae urosepsis. Frontiers Media S.A. 2022-05-17 /pmc/articles/PMC9152446/ /pubmed/35656000 http://dx.doi.org/10.3389/fmicb.2022.893737 Text en Copyright © 2022 Ruwisch, Fischer, Häbel, Laenger and Bollmann. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Ruwisch, Jannik
Fischer, Bettina
Häbel, Lea
Laenger, Florian
Bollmann, Benjamin-Alexander
A Case Report and Review of the Literature: Infectious Aneurysm Formation in the Pulmonary Arteries—A Rare but Perilous Sequela of Persisting Infection With Klebsiella pneumoniae
title A Case Report and Review of the Literature: Infectious Aneurysm Formation in the Pulmonary Arteries—A Rare but Perilous Sequela of Persisting Infection With Klebsiella pneumoniae
title_full A Case Report and Review of the Literature: Infectious Aneurysm Formation in the Pulmonary Arteries—A Rare but Perilous Sequela of Persisting Infection With Klebsiella pneumoniae
title_fullStr A Case Report and Review of the Literature: Infectious Aneurysm Formation in the Pulmonary Arteries—A Rare but Perilous Sequela of Persisting Infection With Klebsiella pneumoniae
title_full_unstemmed A Case Report and Review of the Literature: Infectious Aneurysm Formation in the Pulmonary Arteries—A Rare but Perilous Sequela of Persisting Infection With Klebsiella pneumoniae
title_short A Case Report and Review of the Literature: Infectious Aneurysm Formation in the Pulmonary Arteries—A Rare but Perilous Sequela of Persisting Infection With Klebsiella pneumoniae
title_sort case report and review of the literature: infectious aneurysm formation in the pulmonary arteries—a rare but perilous sequela of persisting infection with klebsiella pneumoniae
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152446/
https://www.ncbi.nlm.nih.gov/pubmed/35656000
http://dx.doi.org/10.3389/fmicb.2022.893737
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