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RNF152 negatively regulates Wnt/β-catenin signaling in Xenopus embryos

The Wnt/β-catenin signaling plays crucial roles in early development, tissue homeostasis, stem cells, and cancers. Here, we show that RNF152, an E3 ligase localized to lysosomes, acts as a negative regulator of the Wnt/β-catenin pathway during Xenopus early embryogenesis. Overexpression of wild-type...

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Detalles Bibliográficos
Autores principales:	Yoon, Gang-Ho, Kim, Kyuhee, Park, Dong-Seok, Choi, Sun-Cheol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152578/ https://www.ncbi.nlm.nih.gov/pubmed/35410636 http://dx.doi.org/10.5483/BMBRep.2022.55.5.187

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