COVID-19 therapies: do we see substantial progress?

The appearance of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its spread all over the world is the cause of the coronavirus disease 2019 (COVID-19) pandemic, which has recently resulted in almost 400 million confirmed cases and 6 million deaths, not to mention unknown long-term...

Descripción completa

Detalles Bibliográficos
Autores principales: Matusewicz, Lucyna, Golec, Marlena, Czogalla, Aleksander, Kuliczkowski, Kazimierz, Konka, Adam, Zembala-John, Joanna, Sikorski, Aleksander F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152818/
https://www.ncbi.nlm.nih.gov/pubmed/35641916
http://dx.doi.org/10.1186/s11658-022-00341-9
Descripción
Sumario:The appearance of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its spread all over the world is the cause of the coronavirus disease 2019 (COVID-19) pandemic, which has recently resulted in almost 400 million confirmed cases and 6 million deaths, not to mention unknown long-term or persistent side effects in convalescent individuals. In this short review, we discuss approaches to treat COVID-19 that are based on current knowledge of the mechanisms of viral cell receptor recognition, virus–host membrane fusion, and inhibition of viral RNA and viral assembly. Despite enormous progress in antiviral therapy and prevention, new effective therapies are still in great demand.

Ejemplares similares