Delayed-onset Organizing Pneumonia Emerging after Recovery from Coronavirus Disease 2019: A Report of Three Cases Diagnosed Using Transbronchial Cryobiopsy and a Review of the Literature

We present three cases with an atypical clinical course of organizing pneumonia (OP) secondary to coronavirus disease 2019 (COVID-19). Three patients were discharged with satisfactory improvement after standard steroid therapy for COVID-19. Shortly after the completion of treatment, the patients exp...

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Detalles Bibliográficos
Autores principales: Nakakubo, Sho, Kamada, Keisuke, Yamashita, Yu, Nakamura, Junichi, Matsumoto, Munehiro, Horii, Hiroshi, Sato, Kazuki, Morinaga, Daisuke, Suzuki, Masaru, Okazaki, Nanase, Takakuwa, Emi, Matsuno, Yoshihiro, Konno, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152860/
https://www.ncbi.nlm.nih.gov/pubmed/35249922
http://dx.doi.org/10.2169/internalmedicine.9016-21
Descripción
Sumario:We present three cases with an atypical clinical course of organizing pneumonia (OP) secondary to coronavirus disease 2019 (COVID-19). Three patients were discharged with satisfactory improvement after standard steroid therapy for COVID-19. Shortly after the completion of treatment, the patients experienced a flare-up of symptoms. Imaging results showed new lesions in the lungs. Transbronchial lung cryobiopsy showed histological findings consistent with OP in all cases. Steroids were administered, and a good therapeutic response was observed. This report is the first to describe pathologically confirmed OP that developed after recovery from COVID-19. Careful follow-up is advisable for patients who have recovered from COVID-19.

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