Rationale and design of a multicentre, 12-week, randomised, double-blind, placebo-controlled, parallel-group, investigator-initiated trial to investigate the efficacy and safety of elobixibat for chronic constipation

INTRODUCTION: Chronic constipation (CC) is a functional disorder that negatively impacts the quality of life of patients. This is a protocol for a multicentre, 12-week, randomised, double-blind, placebo-controlled study to test the efficacy and safety of elobixibat (EXB) versus placebo in patients w...

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Detalles Bibliográficos
Autores principales: Tanaka, Kosuke, Kessoku, Takaomi, Yamamoto, Atsushi, Takahashi, Kota, Kasai, Yuki, Ozaki, Anna, Iwaki, Michihiro, Kobayashi, Takashi, Yoshihara, Tsutomu, Misawa, Noboru, Kato, Takayuki, Arimoto, Jun, Fuyuki, Akiko, Sakai, Eiji, Higurashi, Takuma, Chiba, Hideyuki, Hosono, Kunihiro, Yoneda, Masato, Iwasaki, Tomoyuki, Kurihashi, Takeo, Nakatogawa, Machiko, Suzuki, Ayao, Taguri, Masataka, Oyamada, Shunsuke, Ariyoshi, Keisuke, Kobayashi, Noritoshi, Ichikawa, Yasushi, Nakajima, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Gastroenterology and Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152941/
https://www.ncbi.nlm.nih.gov/pubmed/35636802
http://dx.doi.org/10.1136/bmjopen-2021-060704

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