Cargando…

Transforming growth factor-β signaling modifies the hematopoietic acute inflammatory response to drive bone marrow failure

Bone marrow failure syndromes are characterized by ineffective hematopoiesis due to impaired fitness of hematopoietic stem cells. They can be acquired during bone marrow stress or innate and are associated with driver genetic mutations. Patients with a bone marrow failure syndrome are at higher risk...

Descripción completa

Detalles Bibliográficos
Autores principales: Javier, Jose, Hinge, Ashwini, Bartram, James, Xu, Juying, Filippi, Marie-Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152956/
https://www.ncbi.nlm.nih.gov/pubmed/34706493
http://dx.doi.org/10.3324/haematol.2020.273292