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Transforming growth factor-β signaling modifies the hematopoietic acute inflammatory response to drive bone marrow failure
Bone marrow failure syndromes are characterized by ineffective hematopoiesis due to impaired fitness of hematopoietic stem cells. They can be acquired during bone marrow stress or innate and are associated with driver genetic mutations. Patients with a bone marrow failure syndrome are at higher risk...
Autores principales: | Javier, Jose, Hinge, Ashwini, Bartram, James, Xu, Juying, Filippi, Marie-Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152956/ https://www.ncbi.nlm.nih.gov/pubmed/34706493 http://dx.doi.org/10.3324/haematol.2020.273292 |
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