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Type 1 interferon to prevent leukemia relapse after allogeneic transplantation

A potent graft-versus-leukemia (GVL) response is crucial in preventing relapse, the major impediment to successful allogeneic hematopoietic cell transplantation (HCT). In preclinical studies, type 1 interferon (IFN-α) enhanced cross-presentation of leukemia-specific antigens by CD8α dendritic cells...

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Detalles Bibliográficos
Autores principales: Magenau, John M., Peltier, Dan, Riwes, Mary, Pawarode, Attaphol, Parkin, Brian, Braun, Thomas, Anand, Sarah, Ghosh, Monalisa, Maciejewski, John, Yanik, Gregory, Choi, Sung Won, Talpaz, Moshe, Reddy, Pavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152997/
https://www.ncbi.nlm.nih.gov/pubmed/34607341
http://dx.doi.org/10.1182/bloodadvances.2021004908