Restriction of HIV-1 infection in sickle cell trait

Patients with sickle cell disease (SCD) have a lower risk for HIV-1 infection. We reported restriction of ex vivo HIV-1 infection in SCD peripheral blood mononuclear cells (PBMCs) that was due, in part, to the upregulation of antiviral, inflammatory, and hemolytic factors, including heme oxygenase-1...

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Detalles Bibliográficos
Autores principales: Kumari, Namita, Nouraie, Mehdi, Ahmad, Asrar, Lassiter, Hatajai, Khan, Javed, Diaz, Sharmin, Afangbedji, Nowah, Wang, Songping, Houston, Patricia E., Ammosova, Tatiana, de Mulder Rougvie, Miguel, Rana, Sohail, Nixon, Douglas F., Anastos, Kathryn, Lazar, Jason, French, Audrey L., Gange, Stephen, Adimora, Adaora A., Weitzmann, M. Neale, Fischl, Margaret, Kempf, Mirjam-Colette, Kassaye, Seble, Taylor, James G., Nekhai, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Red Cells, Iron, and Erythropoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153004/
https://www.ncbi.nlm.nih.gov/pubmed/34496009
http://dx.doi.org/10.1182/bloodadvances.2021004247

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