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CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes
CBFB-MYH11 transcripts and KIT mutations predict relapse in AML. High-risk CBFB-MYH11 transcripts are associated with distinct transcriptional landscapes and upregulation of early hematopoiesis genes.
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153007/ https://www.ncbi.nlm.nih.gov/pubmed/34547772 http://dx.doi.org/10.1182/bloodadvances.2021004965 |
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author | Huang, Benjamin J. Smith, Jenny L. Wang, Yi-Cheng Taghizadeh, Kassra Leonti, Amanda R. Ries, Rhonda E. Liu, Yanling Kolekar, Pandurang Tarlock, Katherine Gerbing, Robert Crowgey, Erin Furlan, Scott N. Shaw, Timothy I. Hagiwara, Kohei Wei, Lisa Cooper, Todd M. Gamis, Alan S. Aplenc, Richard Kolb, E. Anders Farrar, Jason E. Triche, Timothy Alonzo, Todd A. Ma, Xiaotu Meshinchi, Soheil |
author_facet | Huang, Benjamin J. Smith, Jenny L. Wang, Yi-Cheng Taghizadeh, Kassra Leonti, Amanda R. Ries, Rhonda E. Liu, Yanling Kolekar, Pandurang Tarlock, Katherine Gerbing, Robert Crowgey, Erin Furlan, Scott N. Shaw, Timothy I. Hagiwara, Kohei Wei, Lisa Cooper, Todd M. Gamis, Alan S. Aplenc, Richard Kolb, E. Anders Farrar, Jason E. Triche, Timothy Alonzo, Todd A. Ma, Xiaotu Meshinchi, Soheil |
author_sort | Huang, Benjamin J. |
collection | PubMed |
description | CBFB-MYH11 transcripts and KIT mutations predict relapse in AML. High-risk CBFB-MYH11 transcripts are associated with distinct transcriptional landscapes and upregulation of early hematopoiesis genes. |
format | Online Article Text |
id | pubmed-9153007 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | American Society of Hematology |
record_format | MEDLINE/PubMed |
spelling | pubmed-91530072022-05-31 CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes Huang, Benjamin J. Smith, Jenny L. Wang, Yi-Cheng Taghizadeh, Kassra Leonti, Amanda R. Ries, Rhonda E. Liu, Yanling Kolekar, Pandurang Tarlock, Katherine Gerbing, Robert Crowgey, Erin Furlan, Scott N. Shaw, Timothy I. Hagiwara, Kohei Wei, Lisa Cooper, Todd M. Gamis, Alan S. Aplenc, Richard Kolb, E. Anders Farrar, Jason E. Triche, Timothy Alonzo, Todd A. Ma, Xiaotu Meshinchi, Soheil Blood Adv Stimulus Report CBFB-MYH11 transcripts and KIT mutations predict relapse in AML. High-risk CBFB-MYH11 transcripts are associated with distinct transcriptional landscapes and upregulation of early hematopoiesis genes. American Society of Hematology 2021-11-30 /pmc/articles/PMC9153007/ /pubmed/34547772 http://dx.doi.org/10.1182/bloodadvances.2021004965 Text en © 2021 by The American Society of Hematology. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved. |
spellingShingle | Stimulus Report Huang, Benjamin J. Smith, Jenny L. Wang, Yi-Cheng Taghizadeh, Kassra Leonti, Amanda R. Ries, Rhonda E. Liu, Yanling Kolekar, Pandurang Tarlock, Katherine Gerbing, Robert Crowgey, Erin Furlan, Scott N. Shaw, Timothy I. Hagiwara, Kohei Wei, Lisa Cooper, Todd M. Gamis, Alan S. Aplenc, Richard Kolb, E. Anders Farrar, Jason E. Triche, Timothy Alonzo, Todd A. Ma, Xiaotu Meshinchi, Soheil CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes |
title | CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes |
title_full | CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes |
title_fullStr | CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes |
title_full_unstemmed | CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes |
title_short | CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes |
title_sort | cbfb-myh11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes |
topic | Stimulus Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153007/ https://www.ncbi.nlm.nih.gov/pubmed/34547772 http://dx.doi.org/10.1182/bloodadvances.2021004965 |
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