Ablation of collagen VI leads to the release of platelets with altered function

Hemostatic abnormalities and impaired platelet function have been described in patients affected by connective tissue disorders. We observed a moderate bleeding tendency in patients affected by collagen VI–related disorders and investigated the defects in platelet functionality, whose mechanisms are...

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Detalles Bibliográficos
Autores principales: Abbonante, Vittorio, Gruppi, Cristian, Battiston, Monica, Zulian, Alessandra, Di Buduo, Christian Andrea, Chrisam, Martina, Sereni, Lucia, Laurent, Pierre-Alexandre, Semplicini, Claudio, Lombardi, Elisabetta, Mazzucato, Mario, Moccia, Francesco, Petronilli, Valeria, Villa, Anna, Bello, Luca, Pegoraro, Elena, Bernardi, Paolo, Braghetta, Paola, De Marco, Luigi, Bonaldo, Paolo, Balduini, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153009/
https://www.ncbi.nlm.nih.gov/pubmed/34547769
http://dx.doi.org/10.1182/bloodadvances.2020002671

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