A novel 3D culture model recapitulates primary FL B-cell features and promotes their survival

Non-Hodgkin B-cell lymphomas (B-NHL) mainly develop within lymph nodes as aggregates of tumor cells densely packed with their surrounding microenvironment, creating a tumor niche specific to each lymphoma subtypes. In vitro preclinical models mimicking biomechanical forces, cellular microenvironment...

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Detalles Bibliográficos
Autores principales: Lamaison, Claire, Latour, Simon, Hélaine, Nelson, Le Morvan, Valérie, Saint-Vanne, Julien, Mahouche, Isabelle, Monvoisin, Céline, Dussert, Christelle, Andrique, Laëtitia, Deleurme, Laurent, Dessauge, Elise, Pangault, Céline, Baulande, Sylvain, Legoix, Patricia, Seffals, Marine, Broca-Brisson, Léa, Alessandri, Kévin, Carlotti, Martina, Soubeyran, Pierre, Merlio, Jean-Philippe, Mourcin, Frédéric, Nassoy, Pierre, Recher, Gaëlle, Tarte, Karin, Bresson-Bepoldin, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153016/
https://www.ncbi.nlm.nih.gov/pubmed/34555842
http://dx.doi.org/10.1182/bloodadvances.2020003949

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