The H3K27M mutation alters stem cell growth, epigenetic regulation, and differentiation potential

BACKGROUND: Neurodevelopmental disorders increase brain tumor risk, suggesting that normal brain development may have protective properties. Mutations in epigenetic regulators are common in pediatric brain tumors, highlighting a potentially central role for disrupted epigenetic regulation of normal...

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Detalles Bibliográficos
Autores principales: Kfoury-Beaumont, N., Prakasam, R., Pondugula, S., Lagas, J. S., Matkovich, S., Gontarz, P., Yang, L., Yano, H., Kim, A. H., Rubin, J. B., Kroll, K. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153095/
https://www.ncbi.nlm.nih.gov/pubmed/35637482
http://dx.doi.org/10.1186/s12915-022-01324-0

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