Cargando…

Bone morphogenetic protein signaling regulation of AMPK and PI3K in lung cancer cells and C. elegans

BACKGROUND: Bone morphogenetic protein (BMP) is a phylogenetically conserved signaling pathway required for development that is aberrantly expressed in several age-related diseases including cancer, Alzheimer’s disease, obesity, and cardiovascular disease. Aberrant BMP signaling in mice leads to obe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vora, Mehul, Mondal, Arindam, Jia, Dongxuan, Gaddipati, Pranya, Akel, Moumen, Gilleran, John, Roberge, Jacques, Rongo, Christopher, Langenfeld, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153151/ https://www.ncbi.nlm.nih.gov/pubmed/35641992 http://dx.doi.org/10.1186/s13578-022-00817-3

Ejemplares similares

Bone morphogenetic protein inhibitors and mitochondria targeting agents synergistically induce apoptosis-inducing factor (AIF) caspase-independent cell death in lung cancer cells
por: Mondal, Arindam, et al.
Publicado: (2022)

Bone morphogenetic protein receptor 2 inhibition destabilizes microtubules promoting the activation of lysosomes and cell death of lung cancer cells
por: Mondal, Arindam, et al.
Publicado: (2021)

Ym155 localizes to the mitochondria leading to mitochondria dysfunction and activation of AMPK that inhibits BMP signaling in lung cancer cells
por: Mondal, Arindam, et al.
Publicado: (2022)

Targeting bone morphogenetic protein receptor 2 sensitizes lung cancer cells to TRAIL by increasing cytosolic Smac/DIABLO and the downregulation of X-linked inhibitor of apoptosis protein
por: NeMoyer, Rachel, et al.
Publicado: (2019)

Inhibition of BMP and of TGFβ receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death
por: Augeri, Dave J., et al.
Publicado: (2016)

The hypoxia response pathway promotes PEP carboxykinase and gluconeogenesis in C. elegans
por: Vora, Mehul, et al.
Publicado: (2022)

Reply to: Potential contribution of PEP carboxykinase-dependent malate dismutation to the hypoxia response in C. elegans
por: Vora, Mehul, et al.
Publicado: (2023)

Bone Morphogenetic Protein Type I Receptor Antagonists Decrease Growth and Induce Cell Death of Lung Cancer Cell Lines
por: Langenfeld, Elaine, et al.
Publicado: (2013)

Small molecule antagonist of the bone morphogenetic protein type I receptors suppresses growth and expression of Id1 and Id3 in lung cancer cells expressing Oct4 or nestin
por: Langenfeld, Elaine, et al.
Publicado: (2013)

An AMPK biosensor for Caenorhabditis elegans
por: Carman, Lynly, et al.
Publicado: (2022)

AMPK exerts dual regulatory effects on the PI3K pathway
por: Tao, Rong, et al.
Publicado: (2010)

Computational modeling and analysis of the morphogenetic domain signaling networks regulating C. elegans embryogenesis
por: Niu, Ben, et al.
Publicado: (2022)

Selection Study for B+- -> (K-+ pi+- pi-+ pi+-)D K+- and B+- -> (K+ K- pi+ pi-)D K+-".
por: Hunt, P, et al.
Publicado: (2009)

Sequence Relationships among C. elegans, D. melanogaster and Human microRNAs Highlight the Extensive Conservation of microRNAs in Biology
por: Ibáñez-Ventoso, Carolina, et al.
Publicado: (2008)

Differential equation and inequalities of the generalized k-Bessel functions
por: Mondal, Saiful R., et al.
Publicado: (2018)

C. elegans SMA-10 regulates BMP receptor trafficking
por: Gleason, Ryan J., et al.
Publicado: (2017)

Acylpyrazoline-Based Third-Generation Selective Antichlamydial Compounds with Enhanced Potency
por: Lu, Bin, et al.
Publicado: (2023)

Calcineurin Antagonizes AMPK to Regulate Lipolysis in Caenorhabditis elegans
por: Wang, Yanli, et al.
Publicado: (2017)

RAB-6.1 and RAB-6.2 Promote Retrograde Transport in C. elegans
por: Zhang, Donglei, et al.
Publicado: (2016)

Differential crosstalk between the AMPK and PI3K/Akt pathways in breast cancer cells of differing genotypes: Leptin inhibits the effectiveness of AMPK activation
por: EL-MASRY, OMAR S., et al.
Publicado: (2015)

Effects of Exercise on AMPK Signaling and Downstream Components to PI3K in Rat with Type 2 Diabetes
por: Cao, Shicheng, et al.
Publicado: (2012)

Metformin alleviates neurocognitive impairment in aging via activation of AMPK/BDNF/PI3K pathway
por: Ameen, Omnia, et al.
Publicado: (2022)

Quercetin ameliorates chicken quality by activating the PI3K/PKB/AMPK signaling pathway in broilers
por: Wang, Mi, et al.
Publicado: (2022)

Human Marfan and Marfan-like Syndrome associated mutations lead to altered trafficking of the Type II TGFβ receptor in Caenorhabditis elegans
por: Lin, Jing, et al.
Publicado: (2019)

CeleST: Computer Vision Software for Quantitative Analysis of C. elegans Swim Behavior Reveals Novel Features of Locomotion
por: Restif, Christophe, et al.
Publicado: (2014)

Deletion of microRNA-80 Activates Dietary Restriction to Extend C. elegans Healthspan and Lifespan
por: Vora, Mehul, et al.
Publicado: (2013)

Genetic interactions between the DBL-1/BMP-like pathway and dpy body size–associated genes in Caenorhabditis elegans
por: Lakdawala, Mohammed Farhan, et al.
Publicado: (2019)

Antidiabetic Effect of Artemether in Db/Db Mice Involves Regulation of AMPK and PI3K/Akt Pathways
por: Bai, Xiaolin, et al.
Publicado: (2020)

Identification of Dihydromyricetin and Metabolites in Serum and Brain Associated with Acute Anti-Ethanol Intoxicating Effects in Mice
por: Carry, Eileen, et al.
Publicado: (2021)

The investigation of $K^+\pi^−, \pi^+K^−$ and $\pi^+\pi^−$ atoms
por: Yazkov, Valeriy
Publicado: (2016)

piRNAs and siRNAs collaborate in Caenorhabditis elegans genome defense
por: Billi, Allison C, et al.
Publicado: (2012)

Caenorhabditis elegans SMA-10/LRIG Is a Conserved Transmembrane Protein that Enhances Bone Morphogenetic Protein Signaling
por: Gumienny, Tina L., et al.
Publicado: (2010)

Neuronal AMPK coordinates mitochondrial energy sensing and hypoxia resistance in C. elegans
por: Berry, Brandon J., et al.
Publicado: (2020)

Synergistic activation of AMPK prevents from polyglutamine-induced toxicity in Caenorhabditis elegans
por: Gómez-Escribano, AP, et al.
Publicado: (2020)

Inhibition of PAR-1 delays aging via activating AMPK in C. elegans
por: Wu, Di, et al.
Publicado: (2020)

Study of the K+K-pi+pi- system centrally produced in the reactions pi+p --> pi+(K+K-pi+pi-)p and pp --> p(K+K-pi+pi-)p at 85 GeV/c
por: Armstrong, T A, et al.
Publicado: (1986)

Caffeic Acid Derivatives Inhibit the Growth of Colon Cancer: Involvement of the PI3-K/Akt and AMPK Signaling Pathways
por: Chiang, En-Pei Isabel, et al.
Publicado: (2014)

Targeting PI3K and AMPKα Signaling Alone or in Combination to Enhance Radiosensitivity of Triple Negative Breast Cancer
por: Johnson, Jeremy, et al.
Publicado: (2020)

EHBP-1 Functions with RAB-10 during Endocytic Recycling in Caenorhabditis elegans
por: Shi, Anbing, et al.
Publicado: (2010)

Observation of $\pi^- K^+$ and $\pi^+ K^-$ atoms
por: Yazkov, Valeriy
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_98to4tctegms9cv15m90pcubdm