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Inhibitors of IFN gene stimulators (STING) improve intestinal ischemia–reperfusion-induced acute lung injury by activating AMPK signaling

BACKGROUND: Acute lung injury (ALI) caused by intestinal ischemia–reperfusion is a life-threatening disease. Interferon gene stimulator (STING) is a cytoplasmic DNA sensor that participates in the initiation of the inflammatory response. This study aims to establish whether C-176 (STING inhibitor) i...

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Detalles Bibliográficos
Autores principales: Yang, Mei, Ma, Yu-Xia, Zhi, Ying, Wang, Hai-Bin, Zhao, Li, Wang, Peng-Sheng, Niu, Jie-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153160/
https://www.ncbi.nlm.nih.gov/pubmed/35642042
http://dx.doi.org/10.1186/s40001-022-00703-1

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