Cargando…

In Silico Identification of Potential Inhibitors of the SARS-CoV-2 Nucleocapsid Through Molecular Docking-Based Drug Repurposing

SARS-CoV-2 is the virus responsible for the COVID-19 pandemic, and its effects on people worldwide continue to grow. Protein-targeted therapeutics are currently unavailable for this virus. As with other coronaviruses, the nucleocapsid (N) protein is the most conserved RNA-binding structural protein...

Descripción completa

Detalles Bibliográficos
Autores principales:	Afreen, Rukhsar, Iqbal, Saleem, Shah, Ab Rauf, Afreen, Heena, Vodwal, Lata, Shkir, Mohd.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153216/ http://dx.doi.org/10.1007/s44229-022-00004-z

Ejemplares similares

Challenges and Perspectives of Polyhydroxyalkanoate Production From Microalgae/Cyanobacteria and Bacteria as Microbial Factories: An Assessment of Hybrid Biological System
por: Afreen, Rukhsar, et al.
Publicado: (2021)

In-silico screening to delineate novel antagonists to SARS-CoV-2 nucleocapsid protein
por: Shahanshah, Mohd Fardeen Husain, et al.
Publicado: (2022)

SARS-CoV-2 nucleocapsid and Nsp3 binding: an in silico study
por: Khan, Muhammad Tahir, et al.
Publicado: (2020)

In silico molecular docking analysis for repurposing therapeutics against multiple proteins from SARS-CoV-2
por: Deshpande, Rujuta R., et al.
Publicado: (2020)

In silico prediction of potential inhibitors for the main protease of SARS-CoV-2 using molecular docking and dynamics simulation based drug-repurposing
por: Kumar, Yogesh, et al.
Publicado: (2020)

In silico prediction of potential inhibitors for SARS-CoV-2 Omicron variant using molecular docking and dynamics simulation-based drug repurposing
por: Mohamed, Eslam A. R., et al.
Publicado: (2023)

In silico molecular docking analysis for repurposing approved antiviral drugs against SARS-CoV-2 main protease
por: Khater, Ibrahim, et al.
Publicado: (2021)

Repurposing benzimidazole and benzothiazole derivatives as potential inhibitors of SARS-CoV-2: DFT, QSAR, molecular docking, molecular dynamics simulation, and in-silico pharmacokinetic and toxicity studies
por: Mohapatra, Ranjan K., et al.
Publicado: (2021)

In Silico Screening of Potential Spike Glycoprotein Inhibitors of SARS-CoV-2 with Drug Repurposing Strategy
por: Wei, Tian-zi, et al.
Publicado: (2020)

Repurposing of SARS-CoV nucleocapsid protein specific nuclease resistant RNA aptamer for therapeutics against SARS-CoV-2
por: Parashar, Nidarshana Chaturvedi, et al.
Publicado: (2020)

Repurposing of Drugs for SARS-CoV-2 Using Inverse Docking Fingerprints
por: Jukič, Marko, et al.
Publicado: (2021)

Indian Ethnomedicinal Phytochemicals as Promising Inhibitors of RNA-Binding Domain of SARS-CoV-2 Nucleocapsid Phosphoprotein: An In Silico Study
por: Muthumanickam, Sankar, et al.
Publicado: (2021)

Evaluation of Internal Adaptation and Marginal Fit of Onlays Fabricated Using Computer-Aided Design (CAD)-Computer-Aided Manufacturing (CAM) and Three-Dimensional Printing Techniques: An In Vitro Study
por: Pasha, Shiraz, et al.
Publicado: (2023)

Drug Repurposing for Candidate SARS-CoV-2 Main Protease Inhibitors by a Novel In Silico Method
por: Sencanski, Milan, et al.
Publicado: (2020)

Identification of potential inhibitors of SARS-CoV-2 S protein–ACE2 interaction by in silico drug repurposing
por: Tristán-Flores, Fabiola E, et al.
Publicado: (2021)

In silico drug repurposing carvedilol and its metabolites against SARS-CoV-2 infection using molecular docking and molecular dynamic simulation approaches
por: Zhang, Chunye, et al.
Publicado: (2023)

The study of antiviral drugs targeting SARS-CoV-2 nucleocapsid and spike proteins through large-scale compound repurposing
por: Hu, Xuqiao, et al.
Publicado: (2021)

Repurposing of known anti-virals as potential inhibitors for SARS-CoV-2 main protease using molecular docking analysis
por: Hakmi, Mohammed, et al.
Publicado: (2020)

Drugs Repurposing Using QSAR, Docking and Molecular Dynamics for Possible Inhibitors of the SARS-CoV-2 M(pro) Protease
por: Tejera, Eduardo, et al.
Publicado: (2020)

A molecular docking study of potential inhibitors and repurposed drugs against SARS-CoV-2 main protease enzyme()
por: Ercan, Selami, et al.
Publicado: (2021)

Drug repurposing for identification of potential spike inhibitors for SARS-CoV-2 using molecular docking and molecular dynamics simulations
por: Lazniewski, Michal, et al.
Publicado: (2022)

Immunized mice naturally process in silico-derived peptides from the nucleocapsid of SARS-CoV-2
por: Campos-Ruíz, Mario Aldair, et al.
Publicado: (2023)

Unlocking potential inhibitors for Bruton's tyrosine kinase through in-silico drug repurposing strategies
por: Alrouji, Mohammed, et al.
Publicado: (2023)

In Silico Drug Repurposing for SARS-CoV-2 Main Proteinase and Spike Proteins
por: Maffucci, Irene, et al.
Publicado: (2020)

SARS-CoV-2 entry inhibitors by dual targeting TMPRSS2 and ACE2: An in silico drug repurposing study
por: Baby, Krishnaprasad, et al.
Publicado: (2021)

Drug repurposing for identification of potential inhibitors against SARS-CoV-2 spike receptor-binding domain: An in silico approach
por: Behera, Santosh Kumar, et al.
Publicado: (2021)

Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2
por: Wang, Yi-Ting, et al.
Publicado: (2022)

Virtual Screening of Repurposed Drugs as Potential Spike Protein Inhibitors of Different SARS-CoV-2 Variants: Molecular Docking Study
por: Eweas, Ahmad F., et al.
Publicado: (2022)

In Silico Screening of Natural Products as Potential Inhibitors of SARS-CoV-2 Using Molecular Docking Simulation
por: Hossain, Rajib, et al.
Publicado: (2021)

Repurposing the inhibitors of COVID-19 key proteins through molecular docking approach
por: Alghamdi, Huda Ahmed, et al.
Publicado: (2021)

Screening of potential inhibitors of COVID-19 with repurposing approach via molecular docking
por: Alizadehmohajer, Negin, et al.
Publicado: (2022)

Photodegradation and In Silico Molecular Docking Study of a Diuretic Drug: Clopamide
por: Gupta, Anamika, et al.
Publicado: (2022)

In-Silico targeting of SARS-CoV-2 NSP6 for drug and natural products repurposing
por: Abdelkader, Ahmed, et al.
Publicado: (2022)

Molecular Docking Reveals Ivermectin and Remdesivir as Potential Repurposed Drugs Against SARS-CoV-2
por: Eweas, Ahmad F., et al.
Publicado: (2021)

Drug repurposing for SARS-CoV-2 main protease: Molecular docking and molecular dynamics investigations
por: Omer, Samia E., et al.
Publicado: (2022)

Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in silico Structure-Based Virtual Screening Approach
por: Choudhary, Shweta, et al.
Publicado: (2020)

Repurposing and computational design of PARP inhibitors as SARS-CoV-2 inhibitors
por: Rampogu, Shailima, et al.
Publicado: (2023)

Prediction of potential inhibitors for RNA-dependent RNA polymerase of SARS-CoV-2 using comprehensive drug repurposing and molecular docking approach
por: Parvez, Md. Sorwer Alam, et al.
Publicado: (2020)

In-silico study of peptide-protein interaction of antimicrobial peptides potentially targeting SARS and SARS-CoV-2 nucleocapsid protein
por: Bansal, Ritu, et al.
Publicado: (2021)

Mechanism and pathophysiology of activated protein C-related factor V leiden in venous thrombosis
por: Yusuf, Mohd, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_25fn0gl10c24hdknflpm4h3tj1