Evaluation of Rapid Antigen Detection Kits for Detection of SARS-CoV-2 B.1.1.529

BACKGROUND: Currently, there is a lack of studies evaluating rapid antigen detection (RAD) kits to detect SARS-CoV-2 B.1.1.529. OBJECTIVE: To evaluate the analytical sensitivity of seven RAD kits to detect SARS-CoV-2 B.1.1.529. STUDY DESIGN: The analytical sensitivity was determined by means of limi...

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Detalles Bibliográficos
Autores principales: Mak, Gannon C. K., Lau, Stephen S. Y., Wong, Kitty K. Y., Lau, C. S., Lam, Edman T. K., Ng, Ken H. L., Chan, Rickjason C. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153237/
http://dx.doi.org/10.1007/s44229-022-00009-8
Descripción
Sumario:BACKGROUND: Currently, there is a lack of studies evaluating rapid antigen detection (RAD) kits to detect SARS-CoV-2 B.1.1.529. OBJECTIVE: To evaluate the analytical sensitivity of seven RAD kits to detect SARS-CoV-2 B.1.1.529. STUDY DESIGN: The analytical sensitivity was determined by means of limit of detection (LOD). A dilution set using a respiratory specimen collected from a COVID-19 patient infected with SARS-CoV-2 B.1.1.529 was prepared. RT-PCR was used as a reference method. RESULTS: The LOD results showed that all seven RAD kits had comparable analytical sensitivity for detection of SARS-CoV-2 B.1.1.529. CONCLUSIONS: The RAD kits selected in the current study may be used for first-line screening of the recently emerged SARS-CoV-2 B.1.1.529.

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