KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4

Kaposi sarcoma-associated herpesvirus (KSHV) establishes a latent infection in the cell nucleus, but where KSHV episomal genomes are tethered and the mechanisms underlying KSHV lytic reactivation are unclear. Here, we study the nuclear microenvironment of KSHV episomes and show that the KSHV latency...

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Detalles Bibliográficos
Autores principales: Kumar, Ashish, Lyu, Yuanzhi, Yanagihashi, Yuichi, Chantarasrivong, Chanikarn, Majerciak, Vladimir, Salemi, Michelle, Wang, Kang-Hsin, Inagaki, Tomoki, Chuang, Frank, Davis, Ryan R., Tepper, Clifford G., Nakano, Kazushi, Izumiya, Chie, Shimoda, Michiko, Nakajima, Ken-ichi, Merleev, Alexander, Zheng, Zhi-Ming, Campbell, Mel, Izumiya, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153692/
https://www.ncbi.nlm.nih.gov/pubmed/35545047
http://dx.doi.org/10.1016/j.celrep.2022.110788

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