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HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation

Ferroptosis, a novel form of regulated cell death characterized by disrupted iron metabolism and the accumulation of lipid peroxides, has exhibited enormous potential in the therapy of cancer particularly clear cell renal cell carcinoma (ccRCC). Luteolin (Lut), a natural flavonoid widely existing in...

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Detalles Bibliográficos
Autores principales: Han, Shangting, Lin, Fangyou, Qi, Yucheng, Liu, Cong, Zhou, Linxiang, Xia, Yuqi, Chen, Kang, Xing, Ji, Liu, Zilin, Yu, Weimin, Zhang, Yunlong, Zhou, Xiangjun, Rao, Ting, Cheng, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153929/
https://www.ncbi.nlm.nih.gov/pubmed/35656025
http://dx.doi.org/10.1155/2022/3846217

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