Analysis of SARS-CoV-2 known and novel subgenomic mRNAs in cell culture, animal model, and clinical samples using LeTRS, a bioinformatic tool to identify unique sequence identifiers

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a complex strategy for the transcription of viral subgenomic mRNAs (sgmRNAs), which are targets for nucleic acid diagnostics. Each of these sgmRNAs has a unique 5′ sequence, the leader–transcriptional regulatory sequence gene junction...

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Detalles Bibliográficos
Autores principales: Dong, Xiaofeng, Penrice-Randal, Rebekah, Goldswain, Hannah, Prince, Tessa, Randle, Nadine, Donovan-Banfield, I'ah, Salguero, Francisco J, Tree, Julia, Vamos, Ecaterina, Nelson, Charlotte, Clark, Jordan, Ryan, Yan, Stewart, James P, Semple, Malcolm G, Baillie, J Kenneth, Openshaw, Peter J M, Turtle, Lance, Matthews, David A, Carroll, Miles W, Darby, Alistair C, Hiscox, Julian A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154083/
https://www.ncbi.nlm.nih.gov/pubmed/35639883
http://dx.doi.org/10.1093/gigascience/giac045

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