A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition

Cryptosporidium is a leading cause of severe diarrhea and diarrheal-related death in children worldwide. As an obligate intracellular parasite, Cryptosporidium relies on intestinal epithelial cells to provide a niche for its growth and survival, but little is known about the contributions that the i...

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Detalles Bibliográficos
Autores principales: Gibson, Alexis R., Sateriale, Adam, Dumaine, Jennifer E., Engiles, Julie B., Pardy, Ryan D., Gullicksrud, Jodi A., O’Dea, Keenan M., Doench, John G., Beiting, Daniel P., Hunter, Christopher A., Striepen, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154123/
https://www.ncbi.nlm.nih.gov/pubmed/35584177
http://dx.doi.org/10.1371/journal.ppat.1010003

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