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Interesting Case of Cutaneous Metastases to Thoracic Skin from Anaplastic Carcinoma of Thyroid: An Unreported Entity in India

Anaplastic thyroid carcinoma is a highly aggressive tumor with 100% mortality that constitutes 1%–2% of thyroid malignancies. Cutaneous metastases from thyroid carcinoma are extremely rare. We report a case of a 68-year-old male with anaplastic thyroid carcinoma with cervical lymph node and thoracic...

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Detalles Bibliográficos
Autores principales: Jemisingh, P, M. MaalikBabu, A.N., Arumugam, V, Palanivel, Nirmaladevi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154144/
https://www.ncbi.nlm.nih.gov/pubmed/35656243
http://dx.doi.org/10.4103/ijd.ijd_271_21
Descripción
Sumario:Anaplastic thyroid carcinoma is a highly aggressive tumor with 100% mortality that constitutes 1%–2% of thyroid malignancies. Cutaneous metastases from thyroid carcinoma are extremely rare. We report a case of a 68-year-old male with anaplastic thyroid carcinoma with cervical lymph node and thoracic cutaneous metastases. Following the diagnosis of anaplastic carcinoma with stage IVB after thorough investigations, he was started on chemotherapy with cisplatin and adriamycin, and also radiotherapy was given subsequently. Dermatological examination showed a single ulcer of size 3 × 2 cm, hard nodules, and plaques of varied sizes present over the anterior chest. Skin biopsy from the nodule showed pleomorphic tumor cells in strands with colloid material and neutrophilic infiltrates in the deep dermis. The present case report demonstrates that thoracic skin metastases can occur from anaplastic thyroid carcinoma with nodules and ulcers and, to our knowledge, this is the first case report of such an extremely rare condition from India.