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Interesting Case of Cutaneous Metastases to Thoracic Skin from Anaplastic Carcinoma of Thyroid: An Unreported Entity in India
Anaplastic thyroid carcinoma is a highly aggressive tumor with 100% mortality that constitutes 1%–2% of thyroid malignancies. Cutaneous metastases from thyroid carcinoma are extremely rare. We report a case of a 68-year-old male with anaplastic thyroid carcinoma with cervical lymph node and thoracic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154144/ https://www.ncbi.nlm.nih.gov/pubmed/35656243 http://dx.doi.org/10.4103/ijd.ijd_271_21 |
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author | Jemisingh, P M. MaalikBabu, A.N. Arumugam, V Palanivel, Nirmaladevi |
author_facet | Jemisingh, P M. MaalikBabu, A.N. Arumugam, V Palanivel, Nirmaladevi |
author_sort | Jemisingh, P |
collection | PubMed |
description | Anaplastic thyroid carcinoma is a highly aggressive tumor with 100% mortality that constitutes 1%–2% of thyroid malignancies. Cutaneous metastases from thyroid carcinoma are extremely rare. We report a case of a 68-year-old male with anaplastic thyroid carcinoma with cervical lymph node and thoracic cutaneous metastases. Following the diagnosis of anaplastic carcinoma with stage IVB after thorough investigations, he was started on chemotherapy with cisplatin and adriamycin, and also radiotherapy was given subsequently. Dermatological examination showed a single ulcer of size 3 × 2 cm, hard nodules, and plaques of varied sizes present over the anterior chest. Skin biopsy from the nodule showed pleomorphic tumor cells in strands with colloid material and neutrophilic infiltrates in the deep dermis. The present case report demonstrates that thoracic skin metastases can occur from anaplastic thyroid carcinoma with nodules and ulcers and, to our knowledge, this is the first case report of such an extremely rare condition from India. |
format | Online Article Text |
id | pubmed-9154144 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-91541442022-06-01 Interesting Case of Cutaneous Metastases to Thoracic Skin from Anaplastic Carcinoma of Thyroid: An Unreported Entity in India Jemisingh, P M. MaalikBabu, A.N. Arumugam, V Palanivel, Nirmaladevi Indian J Dermatol Case Report Anaplastic thyroid carcinoma is a highly aggressive tumor with 100% mortality that constitutes 1%–2% of thyroid malignancies. Cutaneous metastases from thyroid carcinoma are extremely rare. We report a case of a 68-year-old male with anaplastic thyroid carcinoma with cervical lymph node and thoracic cutaneous metastases. Following the diagnosis of anaplastic carcinoma with stage IVB after thorough investigations, he was started on chemotherapy with cisplatin and adriamycin, and also radiotherapy was given subsequently. Dermatological examination showed a single ulcer of size 3 × 2 cm, hard nodules, and plaques of varied sizes present over the anterior chest. Skin biopsy from the nodule showed pleomorphic tumor cells in strands with colloid material and neutrophilic infiltrates in the deep dermis. The present case report demonstrates that thoracic skin metastases can occur from anaplastic thyroid carcinoma with nodules and ulcers and, to our knowledge, this is the first case report of such an extremely rare condition from India. Wolters Kluwer - Medknow 2022 /pmc/articles/PMC9154144/ /pubmed/35656243 http://dx.doi.org/10.4103/ijd.ijd_271_21 Text en Copyright: © 2022 Indian Journal of Dermatology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Jemisingh, P M. MaalikBabu, A.N. Arumugam, V Palanivel, Nirmaladevi Interesting Case of Cutaneous Metastases to Thoracic Skin from Anaplastic Carcinoma of Thyroid: An Unreported Entity in India |
title | Interesting Case of Cutaneous Metastases to Thoracic Skin from Anaplastic Carcinoma of Thyroid: An Unreported Entity in India |
title_full | Interesting Case of Cutaneous Metastases to Thoracic Skin from Anaplastic Carcinoma of Thyroid: An Unreported Entity in India |
title_fullStr | Interesting Case of Cutaneous Metastases to Thoracic Skin from Anaplastic Carcinoma of Thyroid: An Unreported Entity in India |
title_full_unstemmed | Interesting Case of Cutaneous Metastases to Thoracic Skin from Anaplastic Carcinoma of Thyroid: An Unreported Entity in India |
title_short | Interesting Case of Cutaneous Metastases to Thoracic Skin from Anaplastic Carcinoma of Thyroid: An Unreported Entity in India |
title_sort | interesting case of cutaneous metastases to thoracic skin from anaplastic carcinoma of thyroid: an unreported entity in india |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154144/ https://www.ncbi.nlm.nih.gov/pubmed/35656243 http://dx.doi.org/10.4103/ijd.ijd_271_21 |
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