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Dual 5-HT(3) and 5-HT(6) Receptor Antagonist FPPQ Normalizes Phencyclidine-Induced Disruption of Brain Oscillatory Activity in Rats

Schizophrenia is a severe mental disorder featuring psychotic, depressive, and cognitive alterations. Current antipsychotic drugs preferentially target dopamine D(2)-R and/or serotonergic 5-HT(2A/1A)-R. They partly alleviate psychotic symptoms but fail to treat negative symptoms and cognitive defici...

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Detalles Bibliográficos
Autores principales: Castañé, Anna, Cano, Montserrat, Ruiz-Avila, Luis, Miquel-Rio, Lluís, Celada, Pau, Artigas, Francesc, Riga, Maurizio S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154270/
https://www.ncbi.nlm.nih.gov/pubmed/35022720
http://dx.doi.org/10.1093/ijnp/pyac003

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