Correlation Between Genetic Abnormalities in Induced Pluripotent Stem Cell-Derivatives and Abnormal Tissue Formation in Tumorigenicity Tests

Cell therapy using induced pluripotent stem cell (iPSC) derivatives may result in abnormal tissue generation because the cells undergo numerous cycles of mitosis before clinical application, potentially increasing the accumulation of genetic abnormalities. Therefore, genetic tests may predict abnorm...

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Detalles Bibliográficos
Autores principales: Yamamoto, Takako, Sato, Yoji, Yasuda, Satoshi, Shikamura, Masayuki, Tamura, Takashi, Takenaka, Chiemi, Takasu, Naoko, Nomura, Masaki, Dohi, Hiromi, Takahashi, Masayo, Mandai, Michiko, Kanemura, Yonehiro, Nakamura, Masaya, Okano, Hideyuki, Kawamata, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154342/
https://www.ncbi.nlm.nih.gov/pubmed/35445254
http://dx.doi.org/10.1093/stcltm/szac014

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