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SAHA Enhances Differentiation of CD34+CD45+ Hematopoietic Stem and Progenitor Cells from Pluripotent Stem Cells Concomitant with an Increase in Hemogenic Endothelium

Epigenetic modification is an important process during hematopoietic cell differentiation. Histone deacetylase (HDAC) inhibitors have previously been shown to enhance expansion of umbilical cord blood-derived hematopoietic stem cells (HSCs). However, the effect of HDAC inhibitors on pluripotent stem...

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Detalles Bibliográficos
Autores principales:	Shim, Seon-Hui, Tufa, Dejene, Woods, Renee, George, Trahan D, Shank, Tyler, Yingst, Ashley, Lake, Jessica, Cobb, Laura, Jones, Dallas, Jones, Kenneth, Verneris, Michael R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Pluripotent Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154343/ https://www.ncbi.nlm.nih.gov/pubmed/35349707 http://dx.doi.org/10.1093/stcltm/szac012

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