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Development and Introduction of Fexinidazole into the Global Human African Trypanosomiasis Program
In this article, the authors show the strategy used to streamline the introduction of fexinidazole, the first all oral treatment of human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense. The dose range was determined in phase 1 studies and a significant food effect was observed,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Tropical Medicine and Hygiene
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154641/ https://www.ncbi.nlm.nih.gov/pubmed/35292581 http://dx.doi.org/10.4269/ajtmh.21-1176 |