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Reducing lipid bilayer stress by monounsaturated fatty acids protects renal proximal tubules in diabetes
In diabetic patients, dyslipidemia frequently contributes to organ damage such as diabetic kidney disease (DKD). Dyslipidemia is associated with both excessive deposition of triacylglycerol (TAG) in lipid droplets (LDs) and lipotoxicity. Yet, it is unclear how these two effects correlate with each o...
Autores principales: | Pérez-Martí, Albert, Ramakrishnan, Suresh, Li, Jiayi, Dugourd, Aurelien, Molenaar, Martijn R, De La Motte, Luigi R, Grand, Kelli, Mansouri, Anis, Parisot, Mélanie, Lienkamp, Soeren S, Saez-Rodriguez, Julio, Simons, Matias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154741/ https://www.ncbi.nlm.nih.gov/pubmed/35550039 http://dx.doi.org/10.7554/eLife.74391 |
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