Intranasal bovine β-defensin-5 enhances antituberculosis immunity in a mouse model by a novel protein-based respiratory mucosal vaccine

Respiratory mucosal immunization is an effective immunization strategy against tuberculosis (TB), and effective mucosal vaccines require adjuvants that can promote protective immunity without deleterious inflammation. Mucosal BCG (Bacille Calmette-Guerin) is effective, but it causes a severe inflamm...

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Detalles Bibliográficos
Autores principales: Liang, Zhengmin, Li, Hao, Qu, Mengjin, Liu, Yiduo, Wang, Yuanzhi, Wang, Haoran, Dong, Yuhui, Chen, Yulan, Ge, Xin, Zhou, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154763/
https://www.ncbi.nlm.nih.gov/pubmed/35603910
http://dx.doi.org/10.1080/21505594.2022.2080342

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