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The PCOS GWAS Candidate Gene ZNF217 Influences Theca Cell Expression of DENND1A.V2, CYP17A1, and Androgen Production

Polycystic ovary syndrome (PCOS), a common endocrine disorder of women, is characterized by increased ovarian androgen production and anovulatory infertility. Genome-wide association studies (GWAS) have identified more than 20 PCOS candidate loci. One GWAS candidate locus encompasses ZNF217, a zinc...

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Detalles Bibliográficos
Autores principales: Waterbury, Jamaia S, Teves, Maria E, Gaynor, Alison, Han, Angela X, Mavodza, Grace, Newell, Jordan, Strauss, Jerome F, McAllister, Jan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155636/
https://www.ncbi.nlm.nih.gov/pubmed/35668995
http://dx.doi.org/10.1210/jendso/bvac078