Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major

BACKGROUND: The macrophage infectivity potentiator (Mip) protein, which belongs to the immunophilin superfamily, is a peptidyl-prolyl cis/trans isomerase (PPIase) enzyme. Mip has been shown to be important for virulence in a wide range of pathogenic microorganisms. It has previously been demonstrate...

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Detalles Bibliográficos
Autores principales: Iwasaki, Jua, Lorimer, Donald D., Vivoli-Vega, Mirella, Kibble, Emily A., Peacock, Christopher S., Abendroth, Jan, Mayclin, Stephen J., Dranow, David M., Pierce, Phillip G., Fox, David, Lewis, Maria, Bzdyl, Nicole M., Kristensen, Sofie S., Inglis, Timothy J. J., Kahler, Charlene M., Bond, Charles S., Hasenkopf, Anja, Seufert, Florian, Schmitz, Jens, Marshall, Laura E., Scott, Andrew E., Norville, Isobel H., Myler, Peter J., Holzgrabe, Ulrike, Harmer, Nicholas J., Sarkar-Tyson, Mitali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155639/
https://www.ncbi.nlm.nih.gov/pubmed/35245364
http://dx.doi.org/10.1093/jac/dkac065

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