Cargando…

Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease

We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that mink remain positive for viral RNA for days, experience clinical signs and histopathologic changes, and transmit the virus to uninfected recipients. Preparedness is crucial to avoid spread among mink a...

Descripción completa

Detalles Bibliográficos
Autores principales: Virtanen, Jenni, Aaltonen, Kirsi, Kegler, Kristel, Venkat, Vinaya, Niamsap, Thanakorn, Kareinen, Lauri, Malmgren, Rasmus, Kivelä, Olga, Atanasova, Nina, Österlund, Pamela, Smura, Teemu, Sukura, Antti, Strandin, Tomas, Dutra, Lara, Vapalahti, Olli, Nordgren, Heli, Kant, Ravi, Sironen, Tarja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155874/
https://www.ncbi.nlm.nih.gov/pubmed/35608951
http://dx.doi.org/10.3201/eid2806.220328
_version_ 1784718328343822336
author Virtanen, Jenni
Aaltonen, Kirsi
Kegler, Kristel
Venkat, Vinaya
Niamsap, Thanakorn
Kareinen, Lauri
Malmgren, Rasmus
Kivelä, Olga
Atanasova, Nina
Österlund, Pamela
Smura, Teemu
Sukura, Antti
Strandin, Tomas
Dutra, Lara
Vapalahti, Olli
Nordgren, Heli
Kant, Ravi
Sironen, Tarja
author_facet Virtanen, Jenni
Aaltonen, Kirsi
Kegler, Kristel
Venkat, Vinaya
Niamsap, Thanakorn
Kareinen, Lauri
Malmgren, Rasmus
Kivelä, Olga
Atanasova, Nina
Österlund, Pamela
Smura, Teemu
Sukura, Antti
Strandin, Tomas
Dutra, Lara
Vapalahti, Olli
Nordgren, Heli
Kant, Ravi
Sironen, Tarja
author_sort Virtanen, Jenni
collection PubMed
description We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that mink remain positive for viral RNA for days, experience clinical signs and histopathologic changes, and transmit the virus to uninfected recipients. Preparedness is crucial to avoid spread among mink and spillover to human populations.
format Online
Article
Text
id pubmed-9155874
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-91558742022-06-04 Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease Virtanen, Jenni Aaltonen, Kirsi Kegler, Kristel Venkat, Vinaya Niamsap, Thanakorn Kareinen, Lauri Malmgren, Rasmus Kivelä, Olga Atanasova, Nina Österlund, Pamela Smura, Teemu Sukura, Antti Strandin, Tomas Dutra, Lara Vapalahti, Olli Nordgren, Heli Kant, Ravi Sironen, Tarja Emerg Infect Dis Research Letter We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that mink remain positive for viral RNA for days, experience clinical signs and histopathologic changes, and transmit the virus to uninfected recipients. Preparedness is crucial to avoid spread among mink and spillover to human populations. Centers for Disease Control and Prevention 2022-06 /pmc/articles/PMC9155874/ /pubmed/35608951 http://dx.doi.org/10.3201/eid2806.220328 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Virtanen, Jenni
Aaltonen, Kirsi
Kegler, Kristel
Venkat, Vinaya
Niamsap, Thanakorn
Kareinen, Lauri
Malmgren, Rasmus
Kivelä, Olga
Atanasova, Nina
Österlund, Pamela
Smura, Teemu
Sukura, Antti
Strandin, Tomas
Dutra, Lara
Vapalahti, Olli
Nordgren, Heli
Kant, Ravi
Sironen, Tarja
Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease
title Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease
title_full Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease
title_fullStr Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease
title_full_unstemmed Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease
title_short Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease
title_sort experimental infection of mink with sars-cov-2 omicron variant and subsequent clinical disease
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155874/
https://www.ncbi.nlm.nih.gov/pubmed/35608951
http://dx.doi.org/10.3201/eid2806.220328
work_keys_str_mv AT virtanenjenni experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT aaltonenkirsi experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT keglerkristel experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT venkatvinaya experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT niamsapthanakorn experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT kareinenlauri experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT malmgrenrasmus experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT kivelaolga experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT atanasovanina experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT osterlundpamela experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT smurateemu experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT sukuraantti experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT strandintomas experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT dutralara experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT vapalahtiolli experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT nordgrenheli experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT kantravi experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease
AT sironentarja experimentalinfectionofminkwithsarscov2omicronvariantandsubsequentclinicaldisease